What to Expect When You Need an Expectorant (2024)

An expectorant is a type of cough medicine that thins and loosens mucus. These medications are typically used for managing chest congestion, especially when symptoms are caused by a lot of mucus.

Expectorants are a mucoactive class of drugs—those that clear mucus from the airways. Guaifenesin is the most common expectorant and is found inMucinex 404and Robitussin.

In addition to over-the-counter (OTC) liquids, pills, and tablets, there are natural remedies that some people use to thin mucus and relieve congestion.

What to Expect When You Need an Expectorant (1)

Mucinex D vs Mucinex DM: What’s the Difference?

Benefits of Expectorant

Expectorants are commonly used for symptoms of short-term (acute) respiratory tract infections, like the common cold, pneumonia, or bronchitis.

These infections can cause a buildup of phlegm in your throat or lungs. Expectorants thin this phlegm. Once it's loosened, you can cough up the excess mucus, making it easier to breathe.

Expectorants can make you more comfortable, but they do not treat the underlying cause of chest congestion. You may need to use another treatment with an expectorant—such as antibiotics to clear up the illness that is making you congested. You may also need a steroid to reduce inflammation to ease symptoms.

Types of Medicinal Expectorants

There are many brand-name over-the-counter (OTC) products and prescriptions that use different types of medication.

  • Guaifenesin: Guaifenesin is considered the most effective expectorant and is the only medication legally approved as an expectorant. It's available as a brand-name medication (Mucinex, Tussin, etc.) and in generic form.
  • Combination medicines: Some medications combine an expectorant with another type of medication to relieve symptoms. For example, Robitussin DMand Mucinex DM are a combination of guaifenesin and dextromethorphan (cough suppressant). Mucaphed is a combination of guaifenesin and phenylephrine (a decongestant).
  • Potassium iodide: Potassium iodide is often used to treat respiratory issues in people with asthma, chronic bronchitis, or emphysema because it is thought to act as an expectorant, decreasing the thickness of mucus.

Should I Take a Decongestant or an Expectorant?

An expectorant helps with a wet cough, breaking up mucus so you can breathe better. If you don't have phlegm but feel stuffy in your nose and sinuses, a decongestant is better. This will shrink swollen tissue so you can inhale freely.

Robitussin vs. Mucinex: How Do They Compare?

Natural Expectorants

Some home remedies can act like an expectorant to thin secretions. However, there is limited evidence supporting their effectiveness in treating cough and congestion.

Studies of natural remedies may include only animal tests and others consist of small human trials. Do not discontinue prescription medications, and talk to your healthcare provider before using alternative treatment.

Examples of natural expectorants include:

  • Honey: Honey is a popular sore throat remedy and may also help with a cough. It can be taken by spoonful or added to tea. Note that babies under 1 year old cannot have honey.
  • Ginger: Ginger may ease chest congestion and cough when used as lozenges, or add fresh ginger to tea. It might even be more helpful if you include honey, too.
  • Garlic: Garlic might help with common cold symptoms, including a cough. While you can add fresh garlic to hot water to make a soothing drink, the taste might be a little too strong. Instead, try adding it to hot water to create steam you can inhale to help clear up a cough.
  • Eucalyptus: Many natural cough remedies have eucalyptus in them. You can use the oil to make steam to breathe in to help ease congestion and cough, but you should not consume it by mouth.
  • Menthol: Minty cool menthol is another popular natural ingredient in cough and cold products. You can use it to help with a cough as well as make a sore throat feel better.
  • Ivy leaf extract: This traditional medicinal plant contains saponins, which may have expectorant properties. Extracts can be made into cough syrups and taken orally.
  • Water: Believe it or not, simply staying hydrated by drinking plenty of water will go a long way to helping clear up mucus, soothe throat irritation, and calm a cough.

Remember: While many natural cold remedies are considered safe in general, they may not be safe for you to use depending on your health and the medications you take. Always ask your provider or pharmacist before you try a natural remedy or supplement. And consult a healthcare provider if your cough does not get better after you've been treating it at home.

Off-Label Uses of Expectorants

Sometimes, expectorants are used to manage congestion associated with chronic respiratory conditions likechronic obstructive pulmonary disease (COPD)or emphysema. If you have a chronic respiratory condition, you should not use an expectorant unless your healthcare provider recommends it.

Guaifenesin has been explored inthe management of fibromyalgia, but researchers are not sure why it might help and providers do not officially consider it a treatment for the condition.

How the Guaifenesin Protocol May Ease Fibromyalgia Symptoms

Precautions and Contraindications

Talk to your provider before using an expectorant if you are pregnant or breastfeeding. If you have developed any type of allergic reaction or intolerance to expectorants in the past, you should not use them.

You should also be careful when driving or using machinery while you’re taking an expectorant because the medications can make you drowsy or dizzy.

Expectorants often come as combination medications. It’s important to read the labels carefully and make sure you know what all the ingredients are. Even if you can safely take an expectorant, there might be other ingredients in the product that would not be safe for you to take.

Some combination medications also have pain-relieving ingredients in them. If you are already taking another pain reliever like Tylenol, check if the cold product has any pain medicines in it to make sure you don't take too much.

Dosage

If you’re taking an expectorant, follow your healthcare provider’s or pharmacist’s instructions. Always read the medication package carefully and make sure you understand them.

Follow these general guidelines:

  • Do not crush pills.
  • Measure liquid formulations using the measuring tools that come with the medication.
  • Drink plenty of fluids when taking an expectorant.
  • Store your medication according to the package instructions and away from pets and children.

Side Effects

Expectorants do not commonly cause serious side effects. The most common side effects of expectorants include dizziness, drowsiness, and rash.

Combination expectorants are more likely to cause side effects. Dextromethorphan (the main ingredient in Robitussin DM and Mucinex DM) can cause drowsiness, dizziness, nervousness, restlessness, nausea, and vomiting.

Expectorant medications are sometimes combined with dextromethorphan—a drug that may lead to dependence and can also be a drug of abuse.

Phenylephrine (found in Mucaphed) can cause high blood pressure and a slowed heart rate (bradycardia). The drug can also interact with antidepressants and heart medications.

How Do Cough Suppressants Work?

Summary

Your provider might suggest you take an OTC expectorant to help clear up congestion because these medications work to thin mucus and make it easier to cough up.

There are many expectorant products to choose from and some have other medications that help with common cold symptoms in them, too. Check the labels carefully and know all the ingredients that are in a product you plan to take. You should always check with your provider or pharmacist before starting an expectorant.

Keep in mind thathome remedies for a cough and coldcan also help you feel better.

18 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

  1. Nowicki J, Murray MT. Bronchitis and pneumonia. In: Textbook of Natural Medicine. Elsevier; 2020:1196-1201.e1. doi:10.1016/B978-0-323-43044-9.00155-2

  2. The Ohio State University Wexner Medical Center, Parsons J. What does the color of phlegm mean?.

  3. National Library of Medicine. Guaifenesin.

  4. Albrecht HH, Dicpinigaitis PV, Guenin EP. Role of guaifenesin in the management of chronic bronchitis and upper respiratory tract infections.Multidiscip Respir Med. 2017;12:31. Published 2017 Dec 11. doi:10.1186/s40248-017-0113-4

  5. MedlinePlus. Guaifenesin.

  6. National Library of Medicine. SSKI- potassium iodide solution.

  7. Harvard Health. No coughing matter.

  8. Hibatullah Abuelgasim, Albury C, Joseph H.W. Lee. Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis. 2020;26(2):57-64. doi:10.1136/bmjebm-2020-111336

  9. Deepali Jaybhaye, Chandra S, Johar S, Nagre AS. Effect of honey and ginger mixture on productive cough in pediatrics patients. 2022;11(3):237-237. doi:10.18203/2319-2003.ijbcp20221038

  10. Lissiman E, Bhasale AL, Cohen M. Garlic for the common cold.Cochrane Database Syst Rev. 2014;2014(11):CD006206. Published 2014 Nov 11. doi:10.1002/14651858.CD006206.pub4

  11. Her L, Kanjanasilp J, Chaiyakunapruk N, Sawangjit R. Efficacy and safety ofeucalyptusfor relieving cough: A systematic review and meta-analysis of randomized controlled trials.J Integr Complement Med. 2022;28(3):218-226. doi:10.1089/jicm.2021.0226

  12. Eccles R. The powerful placebo effect in cough: relevance to treatment and clinical trials. 2020;198(1):13-21. doi:10.1007/s00408-019-00305-5

  13. Sierocinski E, Holzinger F, Chenot JF. Ivy leaf (Hedera helix) for acute upper respiratory tract infections: an updated systematic review.Eur J Clin Pharmacol. 2021;77(8):1113-1122. doi:10.1007/s00228-021-03090-4

  14. Button B, Goodell HP, Atieh E, et al. Roles of mucus adhesion and cohesion in cough clearance. 2018;115(49):12501-12506. doi:10.1073/pnas.1811787115

  15. Ramos FL, Krahnke JS, Kim V. Clinical issues of mucus accumulation in COPD. Int J Chron Obstruct Pulmon Dis. 2014;9(1):139-150. doi:10.2147/COPD.S38938

  16. London M.The truths and myths of the use of guaifenesin for fibromyalgia.

  17. MedlinePlus. Dextromethorphan.

  18. Food and Drug Administration. Highlights of prescribing information—phenylephrine hydrochloride.

Additional Reading

By Deborah Leader, RN
Deborah Leader RN, PHN, is a registered nurse and medicalwriter who focuses on COPD.

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What to Expect When You Need an Expectorant (2024)
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